Hallo, vielleicht noch nicht zu spät ++/

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19.01.10 21:23

1435 Postings, 3734 Tage njimkoHallo, vielleicht noch nicht zu spät ++/




07.02.10 01:38

1435 Postings, 3734 Tage njimkogeht voran

09.02.10 19:11

1435 Postings, 3734 Tage njimkoSo kann es weiter gehen

10.02.10 09:55

1435 Postings, 3734 Tage njimkoAuf Investorensuche

21 Jan, 2010 10:02 CET

Updated investor presentation

Oslo, 21 January 2010 - Attached is an updated investor presentation of PCIBiotech.  The presentation will be used in meetings with potential investors inLondon today, 21(st) January 2010.Contact information:PCI Biotech Holding ASA, Strandveien 55, N-1366 LysakerPer Walday, CEO, pw@pcibiotech.no,Mobile: +47 917 93 429Bernt-Olav Røttingsnes, CFO, bor@pcibiotech.no,Mobile: +47 913 47 021This information is subject of the disclosure requirements acc. to §5-12 vphl(Norwegian Securities Trading Act)  

19.02.10 19:05

1435 Postings, 3734 Tage njimkoPCI BIOTECH, gefragt!

23.02.10 14:51

1435 Postings, 3734 Tage njimkoDie Aktionärsstruktur


26.02.10 20:00

1435 Postings, 3734 Tage njimkoErholung naht

01.03.10 10:55

1435 Postings, 3734 Tage njimkoWer hier investiert ist Achtung,

es hat sich eine SKS Formation gebildet nach der es mit hoher wahrscheinlichkeit abwärts geht!  

05.03.10 22:15

1435 Postings, 3734 Tage njimkoDie SKS Formation hat sich aufgelöst!

16.03.10 22:57

1435 Postings, 3734 Tage njimkoEs geht wieder kräftig aufwärts

17.03.10 18:49

1435 Postings, 3734 Tage njimkoFinanznachrichten berichtet über positive Studien

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PCI Biotech reported today that it has completed the treatment of the third dose group in the phase I/II study of its proprietary photosensitiser Amphinex® used in combination with the cytotoxic agent bleomycin in cancer patients. Complete clinical regression of all evaluable treated tumours is observed within a few weeks of treatment also on patients at the third dose level, although one patient died of the underlying disease before complete clinical regression could be achieved. No drug-related serious adverse events have been reported.

To date eleven patients have been given a single photochemical internalisation (PCI) treatment with Amphinex®. Patients with osteosarcoma (1) and squamous cell carcinoma (7) of the Head&Neck and adenocarinoma (3) of the breast have been included and the effectiveness of the PCI treatment seems to be similar across all cancers treated so far. The PCI-technology could therefore potentially be used for local treatment of several different cancers. Three serious adverse events have been recorded; however not deemed drug-related by the investigator.

The investigators at University College Hospital (UCH) in London have observed an apparent high specificity for cancer cells of the PCI treatment. Tumours of very different depths have been treated and it seems that mainly the cancer cells are killed by the treatment, leaving the healthy tissue underneath the tumour largely unaffected. In addition, one patient with a tumour under the skin has been effectively treated with superficial illumination without ulceration of the skin.

"The results of treatment in the patients seen so far continue to be very impressive. While this study is primarily aimed at investigating the safety of Amphinex®, the tolerability of normal tissues is an interesting observation that would prove highly beneficial in clinical practice.", says Principal Investigator Colin Hopper at UCH in London.

When activated by light, Amphinex® promotes effective local delivery of a variety of therapeutic molecules, e.g. bleomycin, through triggered endosomal release. The primary objective of the UCH study is to assess the maximum tolerated dose of Amphinex®, in PCI treatment with bleomycin. Secondary objectives include determination of the antitumor activity of the treatment, as well as the pharmacokinetics of Amphinex®. Preliminary analysis of the pharmacokinetic data indicates that Amphinex® has a half-life in blood of about 18 days. Amphinex® also seems to be present in the skin for a prolonged period, but is barely detectable 3 months after administration. The absence of drug related side effects in the study suggests that the slow kinetics does not impose any additional safety concern.

The patients at the fourth dose level of Amphinex® will be treated as soon as possible, and the study is expected to be completed within 2010.

For more information visit: www.pcibiotech.com


PCI Biotech Holding ASA
Per Walday, CEO
Mobile: +47 917 93 429
Bernt-Olav Røttingsnes, CFO
Mobile: +47 913 47 021
International media inquiries:
Schwartz Commuications UK Limited
Richard Hayhurst
Mobile: +44 (0)7950 878 218

30.03.10 00:48

1435 Postings, 3734 Tage njimkoNiveau wieder erreicht

30.03.10 22:34

1435 Postings, 3734 Tage njimkoEs geht weiter

22.04.10 20:48

1435 Postings, 3734 Tage njimkoNews vom 06.04


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