AVI BIOPHARMA - Schweinegrippe-Profiteur

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27.04.09 19:22
5

1219 Postings, 5811 Tage FortunatusAVI BIOPHARMA - Schweinegrippe-Profiteur

AVI Biopharma entwickelt das Grippemittel Neugene, welches laut Tests effektiv gegen verschiedene Grippestämme wirkt.

Wkn: 908085

Outstanding Shares: 85.644.698 Aktien (Stand: 6.3.2009)

 

Die Aktie wird in Deutschland  und an der NASDAQ gehandelt und erzielt bereits Umsätze in Millionenhöhe. Das Unternehmen verfügte zum 31.12.2008 über Assets von über 25 Millionen USD und hatte Schulden von insgesamt ca. 7 Millionen USD. Der Cashbestand beläuft sich auf ca. 11,5 Millionen USD.

http://secfilings.nasdaq.com/...DK&RcvdDate=3%2F10%2F2009&pdf=

 
Seite: 1 | 2 | 3 | 4 | 5 | 6 | 6   
107 Postings ausgeblendet.

02.06.10 19:59

1219 Postings, 5811 Tage FortunatusAVI gibt positive Testergebnisse bekannt

AVI-4658 Demonstrates First Ever Reported Generation of Greater Than 50% Dystrophin-Positive Muscle Fibers in a Patient Following Systemic Administration in Duchenne Muscular Dystrophy; All Patients in Two Highest Dose Cohorts Generated New Dystrophin-Positive Fibers

AVI-4658 Oligomer Demonstrates Dose Response
Conference Call Scheduled Today at 8:30 AM Eastern Time

BOTHELL, WA -- (MARKET WIRE) -- 06/02/10 -- AVI BioPharma, Inc. (NASDAQ: AVII), a developer of RNA-based drugs, today announced topline biopsy data from Study 28, the ongoing Phase 1b/2 clinical trial of AVI-4658, AVI's lead drug candidate being developed as a systemically administered treatment for a substantial subgroup of patients with Duchenne muscular dystrophy (DMD), a genetic muscle wasting disease caused by failure to produce dystrophin. Topline biopsy data from the study demonstrated the first ever reported generation of new dystrophin-positive muscle fibers of more than 50% of normal in a patient with DMD following systemic administration of a drug. All patients in the two highest dose cohorts of the study demonstrated generation of new dystrophin-positive muscle fibers, although treatment responses varied across and within treatment groups. Generation of functional dystrophin is considered critical for successful treatment of DMD, and AVI intends further clinical evaluation of AVI-4658 to help optimize a dosing regimen to achieve more consistent improvements among patients.

Patients completing 12 weeks of treatment with six different doses of AVI-4658 (0.5, 1.0, 2.0, 4.0, 10 or 20 mg/kg) had their muscles biopsied before and after treatment, and analysis of the post treatment biopsy findings include:

Data reported today for the patients in the 10 and 20 mg/kg drug-treatment cohorts completing the 12 weekly doses (8 of 8 patients) showed consistent skipping of exon 51 in the dystrophin mRNA, providing evidence of systemic biologic activity of AVI-4658.
Three patients, one each in the 2.0, 10 and 20 mg/kg cohorts, demonstrated substantial generation of new dystrophin-positive muscle fibers, including the first ever reported generation of dystrophin-positive muscle fibers of more than 50% of normal in a patient following systemic administration of a drug.
All 8 patients in the 10 and 20 mg/kg cohorts demonstrated generation of new dystrophin-positive muscle fibers.
The three patients, one each in the 2.0, 10 and 20 mg/kg cohorts, demonstrating substantial generation of new dystrophin-positive muscle fibers had multiple fold increases in dystrophin protein expression measured by Western blot over baseline, with patients in the 20 mg/kg cohort demonstrating the highest increases. These three patients also had noted increases in dystrophin per fiber.
"These results are very encouraging. The muscle cells of the patients at the higher levels had clear qualitative and quantitative changes in their dystrophin expression and this was not associated with any sign of inflammation or immune response against dystrophin-positive fibers. To look at the muscle biopsies of these treated patients under the microscope, and appreciate the new production of dystrophin compared to the pre-treated muscles, reveals a very different picture from that typically observed in DMD patients," stated Prof. Francesco Muntoni, Professor of Pediatric Neurology and Head of the Dubowitz Neuromuscular Centre at the UCL Institute of Child Health, London, England and the trial's lead investigator. "This trial demonstrates the potential of a systemically administered drug to induce a substantial novel dystrophin protein expression in multiple patients with DMD at levels that may produce a clinically meaningful effect on the course of the disease. Based on these results and on how the patients tolerated the study drug, I believe that AVI-4658 has the potential to become a disease modifying drug in the treatment of DMD."

Study Details

AVI-4658 was generally well tolerated in all Study 28 patients, and there has been no evidence of anti-dystrophin antibodies or T and B cell infiltration. In the patients completing dosing, two serious adverse events (one instance each of post operative nausea and vomiting, and an ankle fracture), both deemed unrelated to AVI-4658, were reported in different patients after they completed their 12-week treatment period and during the 14-week follow-up period of the trial.

Treatment with AVI-4658 in all patients in the 10 and 20 mg/kg cohorts showed consistent skipping of exon 51, which is believed necessary to restore the mRNA reading frame and dystrophin expression in a substantial subgroup of patients with specific mutations. Analysis of post-treatment biopsies by reverse transcription-polymerase chain reaction (RT-PCR) confirmed the new mRNA resulting from the intended skipping, or exclusion, of exon 51.

All 8 patients in the 10 and 20 mg/kg cohorts treated with AVI-4658 demonstrated generation of new dystrophin-positive muscle fibers as measured by immunofluorescent analysis of their muscle biopsies.

Of note, three patients, one patient in each of the 2.0, 10 and 20 mg/kg cohorts, demonstrated substantial generation of new dystrophin-positive muscle fibers, which increased from 1% to 21%, 1% to 15%, and 3% to 55% of normal, respectively, when comparing pre treatment to post treatment samples. These three patients demonstrated a noted increase in dystrophin per fiber as determined by immunofluorescent analysis as well as multiple fold increases in dystrophin protein expression measured by Western blot over baseline. Patients in the 20 mg/kg cohort demonstrated the greatest fold increases when compared to the other cohorts measured by Western blot.

Overall, patients in the 10 and 20 mg/kg cohorts, both quantitatively and qualitatively, had more uniform and widespread dystrophin-positive fiber distribution than patients receiving lower doses. Additionally, responses of patients in the 20 mg/kg cohort appeared better than the patients in the 10 mg/kg cohort.

"Having supported exon-skipping technology for more than a decade and from its earliest stages, we're delighted that AVI BioPharma has demonstrated that systemic administration of an exon-skipping drug can bring a substantial increase in dystrophin-positive muscle fibers in patients with Duchenne muscular dystrophy," says Valerie Cwik M.D., Muscular Dystrophy Association Executive Vice President, Research and Medical Director. "Many questions remain, including optimal dosing, and treatment applicability for specific mutations, but this is clearly an important advance."

Clinical Trial Design and Update

AVI-4658 is an RNA-based therapeutic employing AVI's novel phosphorodiamidate morpholino oligomer (PMO) based chemistry which can work by exon skipping. It is being developed as a systemic treatment for patients with DMD. Study 28 is a Phase 1b/2 open label, dose-ranging, clinical trial assessing the safety, tolerability, pharmacokinetics and exploratory efficacy of AVI-4658 in ambulatory patients with DMD between the ages of 5 and 15 years of age who have an error in the gene coding for dystrophin that can be treated by skipping exon 51. Patients were dosed once per week for 12 weeks by intravenous infusion. Nineteen patients were enrolled in total and assigned to one of six dose cohorts: 0.5, 1.0, 2.0, 4.0, 10.0 or 20.0 mg/kg. After completion of dosing, patients are followed for a further 14 weeks. The primary objective of the trial is to assess the safety of AVI-4658 at these doses over the 26-week duration of the trial. All patients completed dosing. Some patients in the highest dose cohort remain in the 14 week follow-up period.

"The topline results reported today are very promising and suggest an overall very favorable profile, which is important considering that any DMD therapy will likely be chronic, administered to children and potentially life-long. Of particular importance was that AVI-4658 was generally well tolerated as a systemic treatment in all Study 28 patients, which is consistent with our data demonstrating that AVI-4658 was well tolerated in preclinical studies up to an equivalent human dose of approximately 100 mg/kg," stated Stephen B. Shrewsbury, M.D., Senior Vice President and Chief Medical Officer, AVI BioPharma, Inc. "Moving forward, we will complete our data analysis and we intend to review the clinical data with key opinion leaders and work with regulatory authorities to finalize our plans for additional clinical development, including optimizing a dosing regimen to provide a more consistent result across potentially treatable patients."

The clinical trial of AVI-4658 is being conducted in London, UK at the UCL Institute of Child Health / Great Ormond Street Hospital NHS Trust facilities by members of the MDEX Consortium led by Professor Muntoni and by Professor Kate Bushby at the Royal Victoria Infirmary, Newcastle-Upon-Tyne, UK, which is the coordinating center for the European Network of Excellence TREAT-NMD. The clinical costs for the trial are provided, in part, by the UK Medical Research Council.

About Duchenne Muscular Dystrophy
Duchenne Muscular Dystrophy (DMD) is one of the most common fatal genetic disorders to affect children around the world. Approximately one in every 3,500 boys worldwide is affected with DMD. Girls are rarely affected by the disorder. DMD is a devastating and incurable muscle-wasting disease associated with specific inborn errors in the gene that codes for dystrophin, a protein that plays a key structural role in muscle fiber function. Symptoms usually appear in children by age three. Progressive muscle weakness of the legs and pelvis eventually spreads to the arms, neck, and other areas. By age 10, braces may be required for walking, and most patients require full-time use of a wheelchair by age 12. Eventually, this progresses to complete paralysis and increasing difficulty in breathing due to respiratory muscle dysfunction requiring ventilatory support, and cardiac muscle dysfunction leading to heart failure. The condition is terminal and death usually occurs before the age of 30. The outpatient cost of care for a non-ambulatory DMD patient is very high. There is currently no cure for DMD, but for the first time ever there are promising therapies in, or moving into, development.

Conference Call
AVI management will hold a conference call to review the topline biopsy data from the ongoing Phase 1b/2 clinical trial on June 2, 2010, at 8:30 AM Eastern time (5:30 AM Pacific Time).

The conference call may be accessed by dialing 866.202.0886 for domestic callers and 617.213.8841 for international callers. The passcode for the call is 97738469 and please specify to the operator that you would like to join the "AVI BioPharma conference call." The conference call will be webcast live under the events section of AVI's website at www.avibio.com, and will be archived there following the call. Please connect to AVI's website several minutes prior to the start of the broadcast to ensure adequate time for any software download that may be necessary.

About the MDEX Consortium
The MDEX consortium led by Professor Francesco Muntoni, is a multidisciplinary enterprise to promote translational research into muscular dystrophies, and is formed by the clinical groups of Professor Francesco Muntoni (UCL Institute of Child Health) and Professor Kate Bushby and Professor Volker Straub (Newcastle University), and scientists from Imperial College London (Professor Dominic Wells), UCL Institute of Child Health (Dr. Jennifer Morgan), Royal Holloway University of London (Professor George Dickson), Oxford University (Dr. Matthew Wood) and University of Western Australia (Professor Steve Wilton). In addition, the charities Muscular Dystrophy Campaign (MDC), Action Duchenne and Duchenne Family Support Group also participate in the Consortium. For more information, visit www.mdex.org.uk.

About AVI BioPharma
AVI BioPharma is focused on the discovery and development of RNA-based drugs utilizing proprietary derivatives of its antisense chemistry (phosphorodiamidate morpholino oligomers or PMOs) that can be applied to a wide range of diseases and genetic disorders through several distinct mechanisms of action. Unlike other RNA therapeutic approaches, AVI's antisense technology has been used to directly target both messenger RNA (mRNA) and its precursor (pre-mRNA), allowing for both up- and down-regulation of targeted genes and proteins. AVI's RNA-based drug programs are being evaluated for the treatment of Duchenne muscular dystrophy, including an ongoing systemic Phase 1b/2 clinical trial of exon skipping with AVI-4658. AVI's antiviral programs have demonstrated promising outcomes in Ebola Zaire and Marburg Musoke virus infections and may prove applicable to other viral targets such as Junín, influenza, HCV or Dengue viruses. For more information, visit www.avibio.com.  

11.06.10 00:21

1219 Postings, 5811 Tage FortunatusAVI präsentiert sich...

AVI BioPharma to Present at ThinkEquity's Mid Year Check-Up on Healthcare Conference


BOTHELL, WA -- (MARKET WIRE) -- 06/10/10 -- AVI BioPharma, Inc. (NASDAQ: AVII), a developer of RNA-based therapeutics, announced today that the company is scheduled to present at ThinkEquity's Mid Year Check-Up on Healthcare Conference, June 16, 2010, at 1:00 p.m. Eastern Time in New York City. J. David Boyle II, AVI's Interim President and Chief Executive Officer, and Chief Financial Officer, is scheduled to provide a company overview.

The conference presentation will be webcast live under the events section of AVI's website at www.avibio.com, and will be archived there following the presentation. Please connect to AVI's website several minutes prior to the start of the broadcast to ensure adequate time for any software download that may be necessary.

About AVI BioPharma

AVI BioPharma is focused on the discovery and development of RNA-based therapeutics utilizing proprietary derivatives of its antisense chemistry (morpholino-modified phosphorodiamidate oligomers or PMOs) that can be applied to a wide range of diseases and genetic disorders through several distinct mechanisms of action. Unlike other RNA therapeutic approaches, AVI's antisense technology has been used to directly target both messenger RNA (mRNA) and its precursor (pre-mRNA), allowing for both up and down-regulation of targeted genes and proteins. AVI's RNA-based drug programs are being evaluated for the treatment of Duchenne muscular dystrophy, including an ongoing systemic Phase 1b/2 clinical trial of exon skipping with AVI-4658. AVI's antiviral programs have demonstrated promising outcomes in Ebola Zaire and Marburg Musoke virus infections and may prove applicable to other viral targets such as Junín, influenza, HCV or Dengue viruses. For more information, visit www.avibio.com.

"Safe Harbor" Statement under the Private Securities Litigation Reform Act of 1995: The statements that are not historical facts contained in this release are forward-looking statements that involve risks and uncertainties, including, but not limited to, the results of research and development efforts, the results of preclinical and clinical testing, the effect of regulation by the FDA and other agencies, the impact of competitive products, product development, commercialization and technological difficulties, and other risks detailed in the company's Securities and Exchange Commission filings.



Read more: http://www.nasdaq.com//aspxcontent/...0%2F2010+2%3A00PM#ixzz0qUWlbA9B  

20.06.10 22:19
2

35 Postings, 3815 Tage equity holderAVII

Hallo Zusammen

Erst mal, bin neu hier, komme aus der Schweiz und aus einem Schweizer Börsenforum. Ariva scheint mir ein grosses User-Volumen, sowie kompetente Trader drin zu haben. Deshalb entschied ich mich, hier mich mal anzumelden.

Bin seit letzter Woche in AVII investiert. Habe mir AVII genau studiert, TA gemacht, sowie das News-push-Verhalten genau angeschaut, was eigentlich nicht so wichtig ist. Das Orderbook habe ich mir letzte Woche auch eine Weile Tag für Tag angeschaut. Vorerst habe ich mal einen mittleren Einsatz gewagt (<12k). Einige Tage später, also letzten Freitag konnte ich mir das nicht mehr entgehen lassen und habe nochmals investiert.

Die Aktie könnte meiner Meinung nach eine saubere performance hinlegen, daher empfehle ich sich mal den biotech Titel anzuschauen.

http://www.google.com/finance?q=NASDAQ:AVII

PS: Gibt es hier einen Vorstellungsthread?
Manche werden mich bereits wohl kennen, da ich den gleichen Username in einem CH-Forum trage.  

20.06.10 22:32
1

1219 Postings, 5811 Tage FortunatusDas ansteigende Volumen...

...ist mir auch aufgefallen. Es gab allerdings im August des letzten Jahres Tage, da wurden sogar zwei über 10 Millionen und einmal über 20 Millionen an Aktien gehandelt.

http://www.ariva.de/quote/...009-08-31&secu=5314&boerse_id=40

PS: Wenn Du Dich vorstellen möchtest, tue dies doch einfach im Talk-Forum. Du kannst dort gern einen entsprechenden Thread eröffnen.  

20.06.10 23:04
2

1219 Postings, 5811 Tage FortunatusSchöner Aufwärtstrend im Juni

21.06.10 22:54

35 Postings, 3815 Tage equity holderOrderbook erlaubt?

Ich habe hier mal das US-Orderbook gepostet. Leider ist der Beitrag irgendwie völlig weg. Wurde der Beitrag gelöscht, oder ist hier irgendwo ein Fehler unterlaufen. Das Orderbook dürfte ich ja publizieren dürfen , da ich für dieses bezahle.  

21.06.10 22:58
1

1219 Postings, 5811 Tage FortunatusDein Posting...

...ist Dir wohl misslungen...

Wenn es gelöscht worden wäre, würde man dies im Thread sehen. Das Posten des Orderbuches ist m.W. auch erlaubt.

Wieder 2 Millionen Umsatz heute. Nur leider haben wir fast auf Tagestief geschlossen...  

25.06.10 21:06
1

35 Postings, 3815 Tage equity holderAVII

AVII geht momentan mit dem Dow Jones mehr oder weniger mit. Nur heute nicht so ganz. Aber das Interesse ist gemäss Orderbook noch gut. Der Chart zeigt mir einen baldigen starken Aufschwung. Momentan wird ein Support gebildet.


Also eben der Grund für den anstehenden Kursanstieg sind die sehr positiven "trials" des Medikaments. FDA Entscheid wird daher sehr wahrscheinlich positiv ausfallen. Daher wird es sehr wahrscheinlich dann den Run beim Approval nicht riesig geben, da dies langfristig enthalten ist.  

27.06.10 18:47
1

35 Postings, 3815 Tage equity holderAVII Volumen

Gegen Schluss hat AVII kräftig an Volumen zugenommen. Nach Börsenschluss kam ein Volumen von ca. 1 Million zusammen. Eigentlich recht komisch, weil dies nicht üblich, bzw. selten bei AVII ist. Da läuft irgend etwas, so mein Gefühl.  

10.07.10 00:17

1219 Postings, 5811 Tage FortunatusNews-Nachtrag vom 7.7.2010

 

AVI BioPharma Opens Investigational New Drug (IND) Application for AVI-4658 in Duchenne Muscular Dystrophy

 

BOTHELL, WA -- (MARKET WIRE) -- 07/07/10 -- AVI BioPharma, Inc. (NASDAQ: AVII), a developer of RNA-based therapeutics, today announced that following review by the U.S. Food and Drug Administration the Company's Investigational New Drug (IND) application for AVI-4658 is open. AVI-4658 is AVI's lead drug candidate being developed as a systemically administered treatment for a substantial subgroup of patients with Duchenne muscular dystrophy (DMD), a genetic muscle wasting disease caused by failure to produce dystrophin. AVI plans to initiate a Phase 1b/2 clinical trial in DMD in the U.S. this year.

The intended site for the planned U.S. based study is Nationwide Children's Hospital in Columbus, Ohio, with Jerry R. Mendell, M.D. as the Principal Investigator. The clinical program design is being reviewed in consultation with Dr. Mendell, co-investigator Kevin Flanigan, M.D., and other DMD key opinion leaders. It is anticipated that future clinical evaluation will explore increasing doses of AVI-4658 considering the generally well tolerated nature of the drug candidate as exhibited in the clinical and preclinical studies to date, and the substantial, but variable, increases in dystrophin measurements demonstrated in patients with DMD in the U.K. based Phase 1b/2 clinical trial.

"We are actively working with scientific and medical experts and regulatory authorities to finalize plans for our U.S. based Phase 1b/2 study as we complete the collection and analysis of clinical data from the recent U.K. trial of AVI-4658," stated Stephen B. Shrewsbury, M.D., Senior Vice President and Chief Medical Officer, AVI BioPharma, Inc. "The results we have reported to date are very promising and suggest an overall very favorable safety profile. As we continue the clinical evaluation of systemically administered AVI-4658, I remain optimistic about its potential to induce consistent, substantial novel dystrophin protein expression in patients with DMD."

AVI-4658 is an RNA-based therapeutic employing AVI's novel phosphorodiamidate morpholino oligomer (PMO) based chemistry and exon skipping technologies. It is being developed as a systemic treatment for patients with DMD.

About Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy (DMD) is one of the most common fatal genetic disorders to affect children around the world. Approximately one in every 3,500 boys worldwide is affected with DMD. Girls are rarely affected by the disorder. DMD is a devastating and incurable muscle-wasting disease associated with specific inborn errors in the gene that codes for dystrophin, a protein that plays a key structural role in muscle fiber function. Symptoms usually appear in children by age three. Progressive muscle weakness of the legs and pelvis eventually spreads to the arms, neck, and other areas. By age 10, braces may be required for walking, and most patients require full-time use of a wheelchair by age 12. Eventually, this progresses to complete paralysis and increasing difficulty in breathing due to respiratory muscle dysfunction requiring ventilatory support, and cardiac muscle dysfunction leading to heart failure. The condition is terminal and death usually occurs before the age of 30. The outpatient cost of care for a non-ambulatory DMD patient is very high. There is currently no cure for DMD, but for the first time ever there are promising therapies in, or moving into, development.

About AVI BioPharma

AVI BioPharma is focused on the discovery and development of RNA-based medicines utilizing proprietary derivatives of its antisense chemistry (morpholino-modified phosphorodiamidate oligomers or PMOs) that can be applied to a wide range of diseases and genetic disorders through several distinct mechanisms of action. Unlike other RNA therapeutic approaches, AVI's antisense technology has been used to directly target both messenger RNA (mRNA) and its precursor (pre-mRNA), allowing for both up- and down-regulation of targeted genes and proteins. AVI's RNA-based drug programs are being evaluated for the treatment of Duchenne muscular dystrophy, including an ongoing systemic Phase 1b/2 clinical trial of exon skipping with AVI-4658. AVI's antiviral programs have demonstrated promising outcomes in Ebola Zaire and Marburg Musoke virus infections and may prove applicable to other viral targets such as Junín, influenza, HCV or Dengue viruses. For more information, visit www.avibio.com.

"Safe Harbor" Statement under the Private Securities Litigation Reform Act of 1995: The statements that are not historical facts contained in this release are forward-looking statements that involve risks and uncertainties, including, but not limited to, the results of research and development efforts, the results of preclinical and clinical testing, the effect of regulation by the FDA and other agencies, the impact of competitive products, product development, commercialization and technological difficulties, and other risks detailed in the company's Securities and Exchange Commission filings.



Read more: http://www.nasdaq.com/aspx/...00MRKTWIREUSPR____0638257#ixzz0tE4dRu7o

 

20.07.10 01:23
1

1219 Postings, 5811 Tage FortunatusAktie vor Neubewertung?

Jetzt kommt auf jeden Fall mal richtig Geld in die Kasse. Der neue Vertrag mit dem U.S. Department of Defense Chemical and Biological Defense Programm hat ein Volumen von 291 Millionen USD, wobei die Marktkapitalisierung bei gerademal bei ca. 215 Millionen USD liegt.

Hier die Meldung vom 16.07.2010:

"AVI BioPharma Wins $291 Mln Defense Contract - Stocks to Watch


(RTTNews) - AVI BioPharma Inc. (AVII) said it won a $291 million contract from the U.S. Department of Defense Chemical and Biological Defense Program.

The contract was awarded for advanced development of hemorrhagic fever virus therapeutic candidates, AVI-6002 and AVI-6003, for Ebola and Marburg viruses.

As per the contract, AVI Biopharma will get up to $80 million immediately, with possibility of further funding up to $291 million.

AVII closed Thursday's regular trading at $1.63 on Nasdaq. In Friday's pre-market session, the stock is trading up more than 22%.

For comments and feedback: contact editorial@rttnews.com



Read more: http://www.nasdaq.com/aspx/...847RTTRADERUSEQUITY_0631#ixzz0uAp3M2QM"  

20.07.10 08:17
1

2832 Postings, 4409 Tage Der_Pennystockzoc.The trend is your friend... !?!

ariva.de

Der Chart sieht interessant aus... ==> Watchlist

Gru$$
Der Pennystockzocker
-----------
$$$ Der Pennystockzocker $$$ Zocken mit Freude und Erfolg $$$

21.07.10 14:25
1

15990 Postings, 6947 Tage NassieGute News

http://www.thestreet.com/_nasdaq/story/10812353/1/...EE&cm_ite=NA  

21.07.10 22:19

15990 Postings, 6947 Tage NassieKomischer Kursverlauf heute

schließt der Share tatsächlich im Minus.  

21.07.10 22:33

1219 Postings, 5811 Tage FortunatusNa ja,

im Wesentlichen war der Inhalt der Meldung auch schon seit Freitag bekannt...

Ich bleibe hier erstmal längerfristig drin, da es m.M. über kurz oder lang zu einer Neubewertung kommen wird.  

25.07.10 14:56

35 Postings, 3815 Tage equity holderStrategie?

Der Titel ist wohl vielen aus den Augen verloren gegangen. Bei dem Titel muss man aufpassen. Das Interesse ist noch nicht riesig und daher habe ich das Paket gestaffelt gleich beim >20% jump verkauft. Da sind es einfach die News die die Aktie pushen. Ich werde aber wieder bei günstigeren Preisen einsteigen.

AVII, da wird noch einiges an performance dazu kommen.  

07.07.11 17:27

19914 Postings, 3888 Tage Balu4uSehr günstig?

Mal auf die WL nehmen...

 

02.04.12 19:45

2072 Postings, 4916 Tage Joschi307AVI Biopharm. 1,10 $

heute -25% nach gemischten Studienergebnissen

http://www.marketwatch.com/story/...udy-results-2012-04-02?siteid=rss  

26.06.12 08:04

2072 Postings, 4916 Tage Joschi307AVI 0,61 $

Pursuant to Listing Rule 5810(c)(3)(A), AVI has 180 calendar days, or until November 27, 2012, to regain compliance with the minimum bid price requirement. If at any time before this date AVI's common stock has a closing bid price of $1.00 or more for a minimum of 10 consecutive business days, NASDAQ staff will notify AVI that it has regained compliance.

http://www.benzinga.com/news/12/06/2636947/...id-price-non-compliance  

24.07.12 16:08

12558 Postings, 3547 Tage RudiniHammer!

http://www.nasdaq.com/symbol/srpt/real-time

+ 154% zur Zeit!

Hier die News dazu:

http://www.nasdaq.com/article/...en-in-phase-iib-trial-20120724-00584  

24.07.12 16:13

12558 Postings, 3547 Tage RudiniGeile Woche - seit langem -

Gestern: Top Wetten; heute: GWB und AVI...  

06.10.12 20:30

21075 Postings, 3749 Tage wes_check this out

multi-bagger time  
Angehängte Grafik:
srpt3.png (verkleinert auf 52%) vergrößern
srpt3.png

06.10.12 20:56

21075 Postings, 3749 Tage wes_soryyyyyyyyyyyyyyyy

falscher thread! tut mir leid... Gruß  

28.11.12 18:15

1431 Postings, 3803 Tage MeinMottouiii Der Chart sieht sehr gut aus :-)

Wer kennt diese Aktie?  

29.11.12 14:30

1431 Postings, 3803 Tage MeinMottoBin mal gespannt wo die Aktie

dieses Jahr noch hingeht. :-)  

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